GEO DataSets

(Submitter supplied) Pathogenic microorganisms have evolved various strategies to sense and respond to stress in order to establish infection and ensure survival within the host's complex environment. Hypoxia, a metabolic stress factor encountered by aerobic microorganisms during rapid growth, remains poorly understood in terms of pathogen adaptation. Streptococcus suis, a zoonotic pathogen causing meningitis and sepsis, exhibits remarkable adaptability to anaerobic conditions. more...

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28677

6 Samples

Download data: TXT

(Submitter supplied) To investigate the gene transcription profiles of Streptococcus suis in the planktonic state and biofilm state, we provided samples cultured for 8 h in the planktonic state and samples cultured for 24 h in vitro biofilm. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different samples at two time points.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30562

4 Samples

Download data: XLS

(Submitter supplied) RNA sequencing analysis of the transcriptome of the wild type (WT) strain and ΔadcR mutant. The data revealed that genes encoding the Zn acquisition systems were negatively regulated by AdcR.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30562

6 Samples

Download data: XLS

(Submitter supplied) Pathogenic bacteria encounter a variety of stressful host environments during infection. Their responses to meet these challenges protect them from deadly damages and aid in adaption to harmful environments. Bacterial products critical for this protection are therefore interesting as suitable targets for new antimicrobials. To shed light on the complex array of molecular pathways involved in bacterial stress responses we challenged 32 diverse human pathogenic bacteria to 11 infection related stress conditions and catalogued their transcriptomes. more...

Organism:

Campylobacter jejuni; Francisella tularensis; Acinetobacter baumannii; Neisseria gonorrhoeae; Escherichia coli; Shigella flexneri; Aggregatibacter actinomycetemcomitans; Haemophilus influenzae; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Helicobacter pylori; Enterococcus faecalis; Borreliella burgdorferi; Pseudomonas aeruginosa; Legionella pneumophila; Klebsiella pneumoniae; Yersinia pseudotuberculosis; Vibrio cholerae; Streptococcus suis; Streptococcus agalactiae; Streptococcus pneumoniae; Mycobacterium tuberculosis; Burkholderia pseudomallei; Neisseria meningitidis; Staphylococcus epidermidis; Streptococcus pyogenes; Listeria monocytogenes; Salmonella enterica; Achromobacter xylosoxidans

Type:

Expression profiling by high throughput sequencing

30 related Platforms

1122 Samples

Download data: TXT

(Submitter supplied) The transcriptome of the wild type strain and ΔtroR of Streptococcus suis was compared by RNA sequencing analysis. The data revealed that some genes, such as the troABCD operon, were significantly differentially expressed in the ΔtroR mutant.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

6 Samples

Download data: TXT

(Submitter supplied) We explored the transcriptome change of Streptococcus suis in the presence of manganese by RNA sequencing. The data revealed that the genes in the troABCD operon were significantly downregulated in response to manganese.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

6 Samples

Download data: XLSX

(Submitter supplied) We explored the transcriptome change of Streptococcus suis in the presence of ferrous iron and cobalt by RNA sequencing. The data revealed that expression of a lot of genes was altered to respond to ferrous iron and cobalt toxicity. Moreover, most of the genes differentially expressed in response to cobalt are the same as those in response to ferrous iron.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

9 Samples

Download data: XLSX

(Submitter supplied) To reveal the scope of the stk regulation and explore the differences in the regulatory roles of SC-19 and ∆stk, the global gene transcription profiles of the WT and ∆stk strains were determined by RNA-seq analysis.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22539

2 Samples

Download data: TXT